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November 15, 2008

I. Science and Service News Updates
II. Resources: Publications, Toolkits, Other Resources
III. Calls for Public Input
IV. Calls for Applications
V. Calendar of Events
VI. Funding Information
VII. Programmatic Funding Opportunities
VIII. Research Funding Opportunities (PAs and RFAs)

Print Version

Science and News Update

NIMH, U.S. Army Sign MOA to Conduct Groundbreaking Suicide Research

NIMH and the U.S. Army have entered into a memorandum of agreement (MOA) to conduct research that will help the Army reduce the rate of suicides. NIMH Director Thomas R. Insel, M.D., Army Secretary Pete Geren, and Army Chief of Staff Gen. George W. Casey Jr. signed the MOA on October 23, 2008. The MOA allows for a $50-million, multi-year study on suicide and suicidal behavior among soldiers, across all phases of Army service. It will be the largest single study on the subject of suicide that NIMH has ever undertaken.

Science Update: http://www.nimh.nih.gov/science-news/2008/nimh-us-army-sign-moa-to-conduct-groundbreaking-suicide-research.shtml

NIMH: Genomic Dragnet Finds Clues to Likely Suspects in Alzheimer’s—First Family-Based Study of its Kind Taps Large NIMH Sample

In the first study of its kind, researchers have pinpointed four genes likely associated with risk for the most common, late-onset form of Alzheimer’s disease , including a very strong candidate on chromosome 14. NIMH grantees report on their findings in the November issue of the American Journal of Human Genetics.

Science Update: http://www.nimh.nih.gov/science-news/2008/genomic-dragnet-finds-clues-to-likely-suspects-in-alzheimers.shtml

NIMH: Cells May Provide Target for New Anxiety Medications

A specific population of brain cells could provide a target for developing new medications aimed at helping people learn to mute the fears underlying anxiety disorders, according to NIMH-supported scientists. The work was reported in the July 31 issue of the journal Nature.

Science Update: http://www.nimh.nih.gov/science-news/2008/cells-may-provide-target-for-new-anxiety-medications.shtml

NIMH: Anxious and Healthy Adolescents Respond Differently to an Anxiety-provoking Situation

Brain scans show heightened activity among anxious adolescents exposed to an anxiety-provoking situation when compared with normal controls, according to an NIMH study published in the November 2008 issue of the Archives of General Psychiatry.

Science Update: http://www.nimh.nih.gov/science-news/2008/anxious-and-healthy-adolescents-respond-differently-to-an-anxiety-provoking-situation.shtml

NIMH: Genes That Turn on Together Hold Secrets of Brain’s Molecular Instructions—“Guilt by Association” Could Identify Genetic Culprits in Human Illness

For the first time, scientists have mapped groups of genes that turn on together in the human brain, revealing a kind of Rosetta Stone of its molecular organization. These never-before-seen patterns of co-expressed genes hold promise for implicating genetic mechanisms conferring risk for illness through “guilt by association,” say the researchers. NIMH grantees report on their findings in the November 2008 issue of Nature Neuroscience.

Science Update: http://www.nimh.nih.gov/science-news/2008/genes-that-turn-on-together-hold-secrets-of-brains-molecular-instructions.shtml

NIMH: Brain’s Response to Scary Faces Imaged Faster Than You Can Say “Boo!”

Scientists have captured the split-second workings of the brain’s fear circuitry in people viewing frightful faces. NIMH researchers visualized this fleeting activity in the brain’s fear hub, called the amygdala, using a lightning-fast brain imaging technique called magnetoencephalography (MEG). They showed that such rapid, fear-related neural processes can now be studied non-invasively in living humans, with time resolution that other types of scanners can’t even come close to matching.

Science Update: http://www.nimh.nih.gov/science-news/2008/brains-response-to-scary-faces-imaged-faster-than-you-can-say-boo!.shtml

NIDA: Extended Suboxone Treatment Substantially Improves Outcomes for Opioid-Addicted Young Adults

In the first clinical trial of a medication that was used for an extended time to treat opioid addiction in young adults, participants who received counseling and Suboxone (buprenorphine-naloxone) for 12 weeks had substantially better outcomes than those who received the standard treatment of short-term detoxification and counseling. The study, published November 5 in the Journal of the American Medical Association, was conducted through the National Drug Abuse Treatment Clinical Trials Network supported by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH).

Press Release: http://www.nida.nih.gov/newsroom/08/NR11-04.html

New NIH Policy Establishes Goals to Support Scientists Early in Their Careers

The NIH announced a new policy establishing goals to encourage funding for scientists new to NIH and those who are at an early stage in their careers. The involvement of new investigators is considered essential to the vitality of health-related research and has been the focus of several critically important NIH initiatives. NIH is hopeful that this new policy will nurture a new cadre of promising scientists and provide the continued expertise needed to foster the next generation of biomedical research. NIH expects this new policy will level the playing field, allowing new investigators to achieve success rates comparable to those of established scientists submitting new grant applications. Achievement of a comparable success rate should permit the NIH to support 1650 or more New Investigators across all Institutes and Centers in FY 2009, a number equivalent to that achieved in FY 2008.

Press Release: http://www.nih.gov/news/health/oct2008/od-31.htm

NIH: New Program Teaches Preschoolers Reading Skills, Getting Along With Others

A study funded by the NIH and other federal agencies shows that it's possible to teach preschoolers the pre-reading skills they need for later school success, while at the same time fostering the socials skills necessary for making friends and avoiding conflicts with their peers. The findings address long standing concerns on whether preschool education programs should emphasize academic achievement or social and emotional development.

Press Release: http://www.nih.gov/news/health/nov2008/nichd-14.htm

SAMHSA: Promoting Innovation in Financing Mental Health and Substance Abuse Services

The Substance Abuse and Mental Health Services Administration (SAMHSA) announced the creation of a new financing center of excellence. Through the new center, SAMHSA will create a national network of expertise for generating new financing approaches as well as promising practices developed by mental health and substance abuse service programs and policy makers across the country.

Press Release: http://www.samhsa.gov/newsroom/advisories/0811125930.aspx

SAMHSA: Major Report Finds Screening and Early Intervention Program Used in Diverse Health Care Settings Dramatically Reduces Illicit Drug Use among Patients

Report Found a 67.7 Percent Reduction in Illicit Drug Use Over a Six Month Period among People Receiving these Services

The Screening, Brief Intervention, and Referral to Treatment (SBIRT) program can reduce illicit drug use among patients seeking medical care in a wide variety of health care settings such as hospitals, physician offices, and community clinics, a study finds. SBIRT uses a variety of techniques to screen patients seeking medical health for signs of substance abuse. If a patient screens positive for a substance abuse problem immediate steps are taken to help the patient effectively deal with the problem before the patient’s health and well-being deteriorate.

Press Release: http://www.samhsa.gov/newsroom/advisories/0810310048.aspx

Resources: Publications, Toolkits, Other Resources

New on the NIMH Website

Spanish Language Version of ‘Anxiety Disorders’ Now Available Online

The Spanish language version of the NIMH publication that describes the symptoms, causes, and treatments of the major anxiety disorders is available online.

http://www.nimh.nih.gov/health/publications/spanish/trastornos-de-ansiedad/summary.shtml

NIMH Advisory Workgroup Issues Nine Recommendations to Strengthen Research Training

A workgroup of the National Advisory Mental Health Council makes nine specific recommendations to strengthen the Institute’s program in research training in a new report entitled Investing in the Future released on November 1, 2008.

http://www.nimh.nih.gov/about/director/updates/2008/nimh-advisory-workgroup-issues-nine-recommendations-to-strengthen-research-training.shtml

Inside NIMH: Funding News for Current and Future NIMH Awardees

The fall 2008 edition of Inside NIMH is now available.

http://www.nimh.nih.gov/research-funding/newsletter/2008-october-inside-nimh.html

NIH Research Matters: Longer Treatment Improves Outcomes for Opioid-Addicted Youth

Young adults addicted to opioids were more successful at remaining drug-free when they received 12 weeks of treatment with the combination medication buprenorphine-naloxone than those who received the same treatment for only 2 weeks. The findings suggest that longer-term pharmacological treatment, along with counseling, could be beneficial to adolescents who want to break their opioid addictions.

http://www.nih.gov/news/research_matters/november2008/11102008outcomes.htm

NIH News In Health: Holding Their Attention Get the Scoop on ADHD

This NIH News In Health article addresses attention deficit hyperactivity disorder (ADHD).

http://newsinhealth.nih.gov/2008/November/feature1.htm

New on NIDA Website: Latest NIDA NewsScan Available

The NIDA NewScan: NIDA Addiction Research News is a summary of NIDA-funded research findings.

http://www.nida.nih.gov/newsroom/08/NS-11.html

New SAMHSA Resources and Reports

Latest SAMHSA News Available: Focus on Resources for Returning Vets

The September-October issue of SAMHSA News reports on an August 2008 conference called Paving the Road Home: Returning Veterans and Behavioral Health, and offers information on treatment for traumatic brain injury and post-traumatic stress disorder, employment, and resources for children of military families, among other topics.

http://www.samhsa.gov/samhsaNewsletter/default.aspx

Assertive Community Treatment: Evidence Based Practices Tool Kit

SAMHSA’s Center for Mental Health Services has made available its Assertive Community Treatment Tool Kit in CD/DVD format. The goal of Assertive Community Treatment is to help people stay out of the hospital and to develop skills for living in the community, so that their mental illness is not the driving force in their lives. Assertive community treatment offers services that are customized to the individual needs of the consumer, delivered by a team of practitioners, and available 24 hours a day.

http://mentalhealth.samhsa.gov/cmhs/CommunitySupport/toolkits/community/

Major Depressive Episode and Treatment for Depression among Veterans Aged 21 to 39

Combined data from SAMHSA's 2004 to 2007 National Surveys on Drug Use and Health indicate than an annual average of 9.3% veterans aged 21 to 39 experienced at least one major depressive episode in the past year. Among veterans aged 21 to 39 with a major depressive episode in the past year, 51.7% reported severe impairment in at least one of four role domains (i.e., home management, work, close relationships with others, and social life) and 23.5% reported very severe impairment in at least one of the domains. More than half of veterans aged 21 to 39 who experienced a major depressive episode in the past year received treatment for depression in the past year.

http://oas.samhsa.gov/2k8/veteransDepressed/veteransDepressed.cfm

Short Employers Cost Savings Briefs

These briefs were created to provide information on the costs of substance use disorders for employers and guidance on how they can enhance health plan administration to lower their costs and increase treatment. These briefs will be very concise arguments based on the technical cost literature to help employers recognize the costly influence of substance use disorders in the workplace and understand what actions they can take to address the problem.

http://ncadistore.samhsa.gov/catalog/productDetails.aspx?ProductID=17943

AHRQ: Hospital Stays Related to Mental Health, 2006

This Statistical Brief from the Agency for Healthcare Research Quality (AHRQ) presents data from the Healthcare Cost and Utilization Project on mental health stays at U.S. community hospitals in 2006. Variations in the characteristics of hospitalizations principally for mental health (MH) conditions as well as stays with MH conditions noted as a secondary condition are examined by age, gender, expected payer, and region. The study findings include one out of every 5 hospital stays (21.3 percent) had either a principal or secondary diagnosis of a mental health condition.

http://www.hcup-us.ahrq.gov/reports/statbriefs/sb62.jsp

AHRQ Research Summaries

Study Provides New Evidence Linking Antidepressants and Risk of Suicide in Depressed Children and Adolescents

Recent studies have raised concerns that antidepressants paradoxically boost the risk of suicidal behavior among depressed children and adolescents (but not adults). A new study of Medicaid-insured adults and children from all 50 States provides additional evidence of these risks. It found a twofold increased risk of suicide attempts among children treated with any antidepressant medications. The study was funded in part by an AHRQ grant to the Center for Education and Research on Therapeutics at Rutgers University.

http://www.ahrq.gov/research/oct08/1008RA2.htm

Medical Clinic Structure Influences Use of Mental Health and Substance Abuse Care by Persons with HIV Disease

Persons with HIV disease commonly suffer from mental health problems and substance abuse, which typically interfere with their treatment and health. The likelihood of these patients receiving treatment for these problems depends, in part, on the structure of their medical clinic, concludes a new study that was supported in part by the AHRQ.

http://www.ahrq.gov/research/oct08/1008RA38.htm

ED: Student Victimization in U. S. Schools Results from the 2005 School Crime Supplement to the National Crime Victimization Survey

This report from the Department of Education provides estimates of student victimization as defined by the 2005 School Crime Supplement to the 2005 National Crime Victimization Survey. It shows that student victims of crime are more likely to report conditions of an unfavorable school climate, security measures at school, and exhibit fear and avoidance behaviors. Additional topics covered in this report include the prevalence and type of student victimization at school and selected characteristics of victims, including their demographic characteristics and school type; and victim and non victim reports of the presence of gangs and weapons and the availability of drugs.

http://nces.ed.gov/pubsearch/pubsinfo.asp?pubid=2009306

NIA: New Edition of Alzheimer's Disease: Unraveling the Mystery Available

The National Institute on Aging (NIA) released a new edition of Alzheimer's Disease: Unraveling the Mystery, an illustrated, 80-page book written for people with Alzheimer's disease (AD), their families, health care professionals, students, and others with an interest in the disease. This update helps readers understand AD, its impact on individuals and society, and research advances to prevent or diminish the effects of the disease. 

http://www.nia.nih.gov/Alzheimers/Publications/Unraveling

Calls for Nominations
 
Calls for Public Input
 
Calls for Applications
 
Calendar of Events

Teleconference: Children's Mental Health Problems and the Need for Social Inclusion

November 18, 2008, 2:00 PM – 3:30 PM (Eastern Time)

SAMHSA’s Resource Center to Promote Acceptance, Dignity and Social Inclusion Associated with Mental Health is sponsoring this free teleconference training to (1) Explore research on social exclusion for children with mental health problems and their families; (2) Offer first-hand accounts from families and children with mental health problems on their experiences with prejudice, misperceptions and negative attitudes; and (3) Provide an overview of strategies that may help to reduce prejudice and increase social inclusion for children and their families.

http://www.stopstigma.samhsa.gov/teleconferences/archive/training/teleconference11082008.aspx

Supporting Children Living with Grief and Trauma: A Multidisciplinary Approach

December 10-11, 2008, Los Angeles, California

This Department of Justice’s Office for Victims of Crime Training and Technical Assistance Center training will focus on the needs of children who experience grief and trauma as a result of homicide and how victim service providers, mental health professionals, and law enforcement can work together to best serve these children. Topics include: (1) The signs of grief and trauma in children affected by a homicidal death and the unique challenges surrounding this experience:

(2) Appropriate intervention strategies with children experiencing grief and trauma in order to make referrals; and (3) Strategies to enhance multidisciplinary responses to the special needs of children who experience grief and trauma.

http://www.sei2003.com/ovcttac2008/LA-SupportingChildren.htm

NIH Summit: The Science of Eliminating Health Disparities

December 16-18, 2008, National Harbor, Maryland

Join the NIH Institutes, Centers, Offices, and their many partners engaged in research on minority health and health disparities to: (1) highlight the research progress of the NIH on health issues among racial/ethnic minority and medically underserved populations; (2) increase awareness and understanding of disparities in health; (3) showcase best-practice models in research, capacity-building, outreach, and integrated strategies to eliminate health disparities; (4) identify strengths and gaps in health disparities research; (5) network and dialogue with the nation’s leading experts on minority health and health disparities.

http://www.nimh.nih.gov/research-funding/scientific-meetings/announcements/2008/nih-summit-the-science-of-eliminating-health-disparities.shtml

2009 National Leadership Summit on Eliminating Racial and Ethnic Disparities in Health

February 25–27, 2009, National Harbor, MD Call for Abstracts Due: November 18, 2008

The 2009 National Leadership Summit on Eliminating Racial and Ethnic Disparities in Health, sponsored by the U.S. Department of Health and Human Services, is built around the five core NPA objectives, which are: (1) Increased awareness of health disparities; (2) Strengthened leadership at all levels; (3) Improved patient-provider communication; (4) Improved cultural and linguistic competency; and (5) Improved coordination and utilization of research and evaluation outcomes.

http://www.omhrc.gov/npasummit2009/

Integrating Services, Integrating Research for Co-Occurring Conditions: A Need for New Views and Action

Washington, DC, March 2-3, 2009

Call for Abstracts Due: December 12, 2008

This multidisciplinary scientific conference, with support from NIDA, NIMH, and the National Institute on Alcohol Abuse and Alcoholism, effort seeks to (1) develop a collaborative research agenda to improve behavioral health services delivery to people across the life span, and (2) engage and partner researchers and other key stakeholders such as consumers, family members, providers, policy makers and communities to contribute to and implement this agenda. An additional goal is to create 'new' research teams comprised of people from different arenas who have not worked together previously. This conference provides a unique venue for behavioral health services researchers – from drug abuse, alcohol use and mental health fields – to come together to tackle a shared dilemma.

http://bhsr.fmhi.usf.edu/

Funding Information

NIH Seeks Proposals for 2009 Director's Pioneer and New Innovator Awards

The NIH welcomes proposals for 2009 NIH Director's Pioneer Awards and New Innovator Awards. Both programs are part of the NIH Roadmap for Medical Research and support exceptionally creative scientists who take highly innovative, potentially high-impact approaches to major challenges in biomedical or behavioral research. NIH expects to make 5 to 10 Pioneer Awards and up to 24 New Innovator Awards in September 2009.

Pioneer Awards provide up to $2.5 million in direct costs over 5 years and are open to scientists at any career stage. More information on Pioneer Awards: http://nihroadmap.nih.gov/pioneer

New Innovator Awards provide up to $1.5 million in direct costs over the same period and are for early career investigators who have not received an NIH regular research (R01) or similar NIH grant. More information on New Innovator Awards: http://nihroadmap.nih.gov/newinnovator

New! NIH Transformative R01 Program

The NIH’s new Transformative R01 Program (T-R01s) will allow highly creative, “out-of-the-box” projects to be supported. The T-R01 Program represents a High Risk/High Reward Demonstration Project in which novel approaches to peer review and program management are to be piloted.

The application submission period is from December 29, 2008 to January 29, 2009.

More information on the Transformative R01 Program: http://nihroadmap.nih.gov/T-R01/

Programmatic Funding Opportunities
 
Research Funding Opportunities (PAs and RFAs)

Medical Management of Older Patients with HIV/AIDS

http://grants.nih.gov/grants/guide/pa-files/PA-09-017.html (R01)

http://grants.nih.gov/grants/guide/pa-files/PA-09-018.html (R03)

http://grants.nih.gov/grants/guide/pa-files/PA-09-019.html (R21)

Selected NIH Request for Applications (RFAs)

[Full listing of NIH RFAs at http://grants2.nih.gov/grants/guide/rfa-files/index.html ]

Education Programs of Excellence in Scientifically Validated Behavioral Treatment (R25)

http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-09-110.html

Brain Imaging Studies of Negative Reinforcement in Humans

http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-09-008.html (R01)

http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-09-009.html (R21)

Secondary Data Analyses for Substance Abuse Research (R21/R33)

http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-09-020.html

 

 

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