| Science
and News Update |
NIMH: Older Medication May
Be More Cost-Effective for Some Patients with Schizophrenia
A new study analyzing the economic implications of the Clinical
Antipsychotic Trials of Intervention Effectiveness (CATIE) concludes
that the older (first generation) antipsychotic medication perphenazine
was less expensive and no less effective than the newer (second generation)
medications used in the trial during initial treatment, suggesting
that older antipsychotics still have a role in treating schizophrenia.
The study, published in the American Journal of Psychiatry on December
1, 2006, was funded by the National Institutes of Health's National
Institute of Mental Health (NIMH).
See press release: http://www.nimh.nih.gov/press/catie-cost-effectiveness.cfm
See NIMH Perspective on Antipsychotic Reimbursement - Using Results
from the CATIE Cost Effectiveness Study: http://www.nimh.nih.gov/about/dirupdate_catie.cfm
See background information on CATIE: http://www.nimh.nih.gov/healthinformation/catie.cfm
|
NIMH: Targeting the Most
Aggressive Children May Be Cost-Effective Prevention of Later Conduct
Disorders
Targeted preventive interventions may help reduce conduct problems
in children displaying the most aggressive or disruptive behaviors.
Such interventions also may be cost-effective when compared to the
personal and societal costs of delinquency and crime that can arise
from untreated childhood conduct disorders. NIMH-funded researchers
provided an analysis of one targeted intervention program in the November
2006 issue of the Archives of General Psychiatry.
See science update: http://www.nimh.nih.gov/press/conductdisorders_prev.cfm
|
NIH: Novel Program Enhances
Dementia Caregivers’ Quality of Life
A multifaceted, personalized intervention can significantly improve
the quality of life for caregivers of people with dementia, new research
published Nov. 21, 2006, in Annals of Internal Medicine has found.
The study, Resources for Enhancing Alzheimer’s Caregiver Health
II (REACH II), is the first randomized, controlled trial to look systematically
at the effectiveness of a multi-component caregiver intervention provided
to ethnically diverse populations. Follow-up studies, the researchers
suggest, should examine how the intervention might be used in communities
through the nation’s existing network of health and aging services.
See press release: http://www.nih.gov/news/pr/nov2006/nia-20.htm
|
NIH: NIH R01 Grant Applications
Go Electronic
Beginning with the February 5, 2007 standard receipt date and beyond,
the National Institutes of Health (NIH) will require applicants to
submit all Research Project Grant R01 applications electronically
— no paper applications will be accepted. This change marks
a major milestone in the NIH’s transition to receive all grant
applications electronically, which began with the electronic submission
of Small Business Innovation Research applications in December 2005.
Since that time, NIH has received over 18,000 unique grant applications
and has engaged in a multi-pronged outreach effort to ensure that
its applicant community adjusts successfully to the new process.
See press release: http://www.nih.gov/news/pr/nov2006/oer-28.htm
|
SAMHSA and Ad Council Unveil
National Mental Health Anti-Stigma Campaign
The Substance Abuse and Mental Health Services Administration (SAMHSA),
in partnership with the Ad Council, will launch a national awareness
public service advertising (PSA) campaign designed to decrease the
negative attitudes that surround mental illness and encourage young
adults to support their friends who are living with mental health
problems. In addition to the campaign launch, the results of a new
HealthStyles survey conducted by SAMHSA and the Centers for Disease
Control & Prevention (CDC) will be announced at the event.
See press release: http://www.samhsa.gov/newsroom/advisories/0611274804.aspx |
SAMHSA-funded Study Shows
Receiving Substance Abuse Treatment within 30 Days Following Detoxification
Lengthens the Time to Subsequent Relapse
More than one-quarter of patients receiving publicly funded substance
abuse detoxification will have a second detoxification readmission
within a year. But if patients receive substance abuse treatment on
two or more days within 30 days of discharge from a detoxification
admission, time to subsequent relapse and readmission lengthens by
40 percent according to findings revealed in a study sponsored by
the Substance Abuse and Mental Health Services Administration (SAMHSA)
and published in the September 2006 issue of the Journal of Substance
Abuse Treatment.
See press release: http://www.samhsa.gov/newsroom/advisories/0611162305.aspx |
FDA: Death, Narcotic Overdose,
and Serious Cardiac Arrhythmias
FDA has reviewed reports of death and life-threatening side effects
such as slowed or stopped breathing, and dangerous changes in heart
beat in patients receiving methadone. These serious side effects may
occur because methadone may build up in the body to a toxic level
if it is taken too often, if the amount taken is too high, or if it
is taken with certain other medicines or supplements. Physicians should
closely monitor patients when converting them from other opioids and
changing the methadone dose, and thoroughly instruct patients how
to take methadone. Healthcare professionals should tell patients to
take no more methadone than has been prescribed without first talking
to their physician.
See press release: http://www.fda.gov/cder/drug/infopage/methadone/default.htm |
| Resources:
Publications, Toolkits, Other Resources |
NIDA: Latest ‘NIDA
Notes’ available
This issue includes the latest research findings from NIDA including:
1) Low-Cost Incentives Improve Outcomes in Stimulant Abuse Treatment;
2) Study Finds Withdrawal No Easier With Ultrarapid Opiate Detox;
3) Buprenorphine Plus Behavioral Therapy Is Effective for Adolescents
With Opioid Addiction; 4) Brain Mechanism Turns Off Cocaine-Related
Memory in Rats; and 5) Marijuana Smoking Is Associated With a Spectrum
of Respiratory Disorders.
http://www.drugabuse.gov/NIDA_Notes/NNIndex.html |
SAMHSA: Nearly Half of all
Patients in Treatment for Both Alcohol and Drugs
The National Survey of Substance Abuse Treatment Services (N-SSATS):
2005 was released by the Substance by the Substance Abuse and Mental
Health Services Administration (SAMHSA). The survey showed that the
proportion of patients in treatment for drug and alcohol abuse made
up nearly half of all clients (47 percent). Also, according to the
survey, on March 31, 2005, 1.08 million people were enrolled in substance
abuse treatment, an 8 percent increase from 1 million in 2000. Of
them, 34 percent were in treatment for drug abuse only, up from 29
percent in 2000. In contrast, clients enrolled in treatment only for
alcohol abuse declined from 23 percent in 2000 to 19 percent in 2005.
See press release: http://www.samhsa.gov/newsroom/advisories/0611290152.aspx |
SAMHSA: New Reports from
the Office of Applied Studies
NSDUH Report: Substance Use Disorder and Serious Psychological Distress
by Employment Status.
This short report is based on SAMHSA's National Survey on Drug Use
and Health (NSDUH), formerly called the National Household Survey
on Drug Abuse (NHSDA). According to the report, among full time employed
adults aged 18 to 64, 10.6% were classified as having a past year
substance use disorder, 10.2% experienced serious psychological distress
during the past year, and 2.4% had co-occurring serious psychological
distress and a substance use disorder. Full time employed males in
this age group were nearly twice as likely to have a past year substance
use disorder than their female counterparts (13.2% vs. 6.9%). In contrast,
females were nearly twice more likely to have experienced serious
psychological distress during the past year than were the males (14.2%
vs. 7.3%). Of the 2.9 million adults aged 18 to 64 employed full time
who had co-occurring serious psychological distress and a substance
use disorder, nearly 60% were not treated for either problem and less
than 5% were treated for both problems.
To read the report: http://oas.samhsa.gov/2k6/employDual/employDual.cfm |
CDC: Toxicology Testing and
Results for Suicide Victims - 13 States, 2004
Few studies have attempted to determine the contribution of substance
use to suicide. To assess toxicology testing practices and to determine
the prevalence of positive results for alcohol or other drugs, CDC
analyzed test results of suicide victims in the 13 states that collected
data for the National Violent Death Reporting System in 2004. The
results underscore the need to continue monitoring toxicology test
results of suicide victims, which might identify patterns of substance
use that can help guide development of effective suicide interventions.
See report: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5546a1.htm |
| |
| Calls
for Public Input |
NIMH: Interagency Autism
Coordinating Committee Call for Public Comment
At the Interagency Autism Coordinating Committee’s (IACC) meeting
on May 9, 2006, it was agreed that it was an opportune time to evaluate
progress on the Autism Research Matrix. NIMH was tasked with conducting
the evaluation, and on September 25th an evaluation meeting was held
that included Panel members who were originally involved with the
development of the matrix, as well as new members who were selected
to broaden the Panel’s expertise. Over the course of the day,
the Panel reviewed the state of autism research, moving section by
section, element by element through the matrix. The results of the
evaluation were reported to the IACC at its November 17th meeting.
The IACC agreed to post the report for comments from the public, and
all comments will be accepted until January 16, 2007.
The draft report is available at: http://www.nimh.nih.gov/autismiacc/index.cfm.
Send comments to
iacc@nih.gov. |
NIH Call for Applications
for 2007 Director’s Council of Public Representatives
The Director of the National Institutes of Health (NIH) is seeking
applicants to fill appointments to the Director’s Council of
Public Representatives (COPR). The COPR advises the NIH Director on
cross-cutting issues related to medical research and health issues
of public interest that ultimately promote individual, family, and
community health. The COPR consists of up to 21 individuals who are
selected from among the diverse communities that benefit from, and
have an interest in, NIH research, programs, and activities. Members
typically serve the COPR for three to four years. To be considered
for the COPR, applicants must have some interest in the work of the
NIH and must be in a position to communicate regularly with the broader
public about COPR and NIH activities. Applicants must also be willing
to fully participate in biannual COPR meetings, regular conference
calls, and working group activities throughout the year. Applications
are due December 14, 2006.
For more information or to obtain an online application, visit the
COPR web site: http://copr.nih.gov/application.asp.
To request an application by mail, contact the COPR Resource Staff
by phone at 301-650-8660, Ext. 136, by fax at 301-650-7172 or by e-mail
at: COPR1@palladianpartners.com. |
NIAAA Call for Comments and
Input on Division of Epidemiology and Prevention Research Strategic
Planning Document
The Division of Epidemiology and Prevention Research (DEPR) of the
National Institute on Alcohol Abuse and Alcoholism (NIAAA) is seeking
input on its strategic planning document, which reviews the epidemiology
and prevention research literature and offers recommendations for
research priorities. The document was reviewed by NIAAA's Extramural
Advisory Board (EAB) on August 16-17, 2006. On the basis of its review,
the EAB will present a series of recommendations to the NIAAA National
Advisory Council in February of 2007. Please send any comments or
suggestions to Ralph Hingson, Sc.D., M.P.H., at rhingson@mail.nih.gov
by December 8, 2006.
View strategic plan: http://www.niaaa.nih.gov/ResearchInformation/ExtramuralResearch/AdvisoryCouncil/DEPRStrategicPlan.htm |
| Calendar
of Events |
National Project Homeless
Connect Week 2006
December 4-8, 2006
Project Homeless Connect is a one-day event sponsored by mayors and
other community leaders designed to provide housing, services, and
hospitality in a convenient one-stop model for people experiencing
homelessness. More than 35 cities have replicated this model. The
Interagency Council on Homelessness will convene several national
conference calls to support cities planning 2006 National Project
Homeless Connect participation. Calls are being convened every 2 weeks
to share best practices and common questions. For more information
on conference calls, send an email to: usichevents@usich.gov
http://www.usich.gov/slocal/NationalProjectHomelessConnectPromo.html |
Teleconference: Trauma and
Adolescence
December 7, 2006, 2:00pm-3:30pm EST
The CMHS-sponsored National Child Traumatic Stress Network is hosting
a free teleconference on trauma and adolescence. More details on the
teleconference will be available soon on the web.
http://www.nctsnet.org/nccts/nav.do?pid=ctr_top_train_tele_sched |
47th Annual NCDEU Meeting
June 11-14, 2007, Boca Raton, Florida
The NCDEU Meeting is a scientific conference that brings together
academic researchers from multiple disciplines involved in clinical
trials, investigators with the pharmaceutical industry, and representatives
from NIMH/NIH and the Food and Drug Administration (FDA) to address
psychopharmacology, clinical trials methodology, and the broader areas
of interventions and services research. Proposals for Workshops and/or
Panels as well as poster abstracts and New Investigator Award applications
must be submitted online.
Workshop and Panel Presentations: Extended to December 1, 2006
New Investigator Applications: January 16, 2007
Poster Presentations: January 16, 2007
http://www.nimh.nih.gov/ncdeu/index.cfm |
NIMH Annual International
Research Conference on the Role of Families in Preventing and Adapting
to HIV/AIDS
July 25-27, 2007, San Francisco, California
This conference is designed to present research findings on family
processes and HIV disease. Objectives include: family processes associated
with the epidemiology of AIDS and high-risk behaviors of family members;
family configuration and functioning as predictors of adaptation at
different stages of HIV/AIDS; stress and coping strategies mobilized
by families infected and affected by HIV and AIDS; family issues of
multiple losses, death, bereavement, child custody and permanency
planning; models for mental health services for families with a life-threatening
disease; and strategies for analyzing family data.
Papers and workshops: March 17, 2007
Posters: June 29, 2007
Registration: June 29, 2007
Note: You may register at the conference. However, you must register
by June 29, 2007 in order to be listed in the Program Book.
http://www.nimh.nih.gov/scientificmeetings/hivaids2007.cfm |
| |
| Funding
Information |
Office of Justice Programs'
Bureau of Justice Assistance: Indian Alcohol and Substance Abuse Program
The Office of Justice Programs' Bureau of Justice Assistance (BJA)
is seeking applicants under its Indian Alcohol and Substance Abuse
Program. The program provides funding and technical assistance to
federally recognized tribes to plan, implement, or enhance tribal
justice strategies to address crime issues related to alcohol and
substance abuse. In FY 2007, priority is placed on addressing methamphetamine
use on tribal lands.
The application deadline is January 4, 2007.
FY 2007 Competitive Grant Announcement: http://www.ojp.usdoj.gov/BJA/grant/07IASAPsol.pdf.
For further information: http://www.ojp.usdoj.gov/BJA/grant/indian.html. |
| Programmatic
Funding Opportunities |
National Trauma Information
and Exchange Program
http://www.grants.gov/search/search.do?oppId=11705&mode=VIEW |
National Communications System
for Runaway and Homeless Youth
http://www.grants.gov/search/search.do?oppId=11688&mode=VIEW |
Statewide Family Network
Grants
http://www.grants.gov/search/search.do?oppId=11506&mode=VIEW |
| Research
Funding Opportunities (PAs and RFAs) |
NIH Program Announcements
(PAs)
[Full listing of NIH PAs at http://grants2.nih.gov/grants/guide/pa-files/index.html] |
Drug Discovery for Nervous
System Disorders (R21)
http://grants.nih.gov/grants/guide/pa-files/PAR-07-049.html |
Molecular genetics of drug
addiction and related co-morbidities (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-073.html |
Secondary Analysis of Existing
Alcohol Epidemiology Data (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-071.html |
Alcohol Use Disorders: Treatment,
Services Research, and Recovery (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-066.html |
Parenting Capacities and
Health Outcomes in Youths and Adolescents (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-061.html |
Methodology and Measurement
in the Behavioral and Social Sciences (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-060.html |
Drug Discovery for Nervous
System Disorders (R01)
http://grants.nih.gov/grants/guide/pa-files/PAR-07-048.html |
Treatment-Emergent Adverse
Effects of Psychotropic Medication (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-078.html |
Pathophysiology and Treatment
Response in Late-Life Mood and Anxiety Disorders (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-077.html |
Research On Adherence To
Interventions For Mental Disorders (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-076.html |
Development of Assays for
high Throughput Drug Screening (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-054.html |
Research On Autism And Autism
Spectrum Disorders (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-085.html |
Women’s Mental Health
in Pregnancy and the Postpartum Period (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-081.html |
Research On The Reduction
And Prevention Of Suicidality (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-079.html |
Collaborative R01s for Clinical
and Services Studies of Mental Disorders, AIDS and Alcohol Use Disorders
(R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-092.html |
Effectiveness, Practice,
And Implementation In CMHS’ Comprehensive Community Mental Health
Services Program for Children and their Families Service Sites (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-091.html |
HIV/AIDS, Severe Mental Illness
And Homelessness (R01)
http://grants.nih.gov/grants/guide/pa-files/PA-07-090.html |
NIH Request for Applications
(RFAs)
[Full listing of NIH RFAs at http://grants2.nih.gov/grants/guide/rfa-files/index.html] |
Brain Imaging Drug Use Prevention
Messages (R21)
http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-07-007.html |
|
Extinction and Pharmacotherapies for Drug Addiction (R03)
http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-07-011.html
|
Collaborative Initiative
on Fetal Alcohol Spectrum Disorders (CIFASD)(U01 and U24)
http://grants.nih.gov/grants/guide/rfa-files/RFA-AA-07-004.html |
Center for Genomic and Phenomic
Studies in Autism (U24)
http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-07-080.html |
